Alcohols and polyols
- (1)
- (55)
- (347)
- (41)
- (4)
- (8)
- (7)
- (55)
- (3)
- (7)
- (18)
- (1)
- (4)
- (156)
- (1)
- (64)
- (28)
- (14)
- (3)
- (1)
- (1)
- (10)
- (3)
- (2)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (6)
- (3)
- (30)
- (4)
- (20)
- (10)
- (2)
- (10)
- (4)
- (5)
- (399)
- (6)
- (102)
- (22)
- (50)
- (31)
- (63)
- (13)
- (14)
- (1)
- (2)
- (1)
- (25)
- (6)
- (4)
- (1)
- (6)
- (1)
- (463)
- (9)
- (46)
- (10)
- (46)
- (6)
- (1)
- (6)
- (13)
- (148)
- (116)
- (8)
- (5)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (4)
- (7)
- (14)
- (2)
- (1)
- (6)
- (5)
- (1)
- (12)
- (21)
- (5)
- (2)
- (2)
- (2)
- (16)
- (2)
- (30)
- (1)
- (4)
- (1)
- (2)
- (1)
- (20)
- (10)
- (4)
- (15)
- (1)
- (4)
- (6)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (4)
- (3)
- (1)
- (28)
- (29)
- (7)
- (3)
- (5)
- (1)
- (36)
- (5)
- (4)
- (2)
- (5)
- (4)
- (17)
- (15)
- (4)
- (5)
- (1)
- (2)
- (5)
- (1)
- (4)
- (37)
- (4)
- (2)
- (6)
- (8)
- (2)
- (2)
- (8)
- (7)
- (7)
- (2)
- (1)
- (1)
- (26)
- (1)
- (1)
- (1)
- (2)
- (1)
- (3)
- (4)
- (2)
- (1)
- (15)
- (12)
- (1)
- (3)
- (2)
- (7)
- (12)
- (1)
- (14)
- (24)
- (1)
- (8)
- (4)
- (1)
- (2)
- (1)
- (22)
- (2)
- (6)
- (5)
- (2)
- (1)
- (5)
- (3)
- (4)
- (24)
- (5)
- (3)
- (5)
- (14)
- (1)
- (1)
- (1)
- (11)
- (3)
- (2)
- (4)
- (11)
- (2)
- (6)
- (4)
- (1)
- (3)
- (6)
- (11)
- (5)
- (4)
- (1)
- (2)
- (11)
- (14)
- (7)
- (2)
- (3)
- (1)
- (3)
- (1)
- (2)
- (1)
- (10)
- (1)
- (2)
- (4)
- (4)
- (1)
- (3)
- (1)
- (3)
- (5)
- (1)
- (1)
- (2)
- (1)
- (10)
- (2)
- (2)
- (3)
- (7)
- (1)
- (1)
- (5)
- (4)
- (1)
- (2)
- (9)
- (4)
- (2)
- (12)
- (4)
- (1)
- (5)
- (4)
- (10)
- (2)
- (5)
- (1)
- (1)
- (1)
- (10)
- (6)
- (1)
- (2)
- (2)
- (6)
- (14)
- (2)
- (4)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (4)
- (2)
- (1)
- (1)
- (4)
- (2)
- (3)
- (2)
- (4)
- (3)
- (1)
- (4)
- (5)
- (1)
- (4)
- (5)
- (9)
- (1)
- (5)
- (5)
- (2)
- (1)
- (1)
- (2)
- (5)
- (3)
- (5)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (4)
- (2)
- (1)
- (2)
- (2)
- (11)
- (9)
- (1)
- (1)
- (2)
- (1)
- (1)
- (3)
- (1)
- (1)
- (10)
- (1)
- (1)
- (1)
- (2)
- (4)
- (11)
- (1)
- (2)
- (4)
- (20)
- (21)
- (2)
- (8)
- (2)
- (3)
- (3)
- (1)
- (8)
- (4)
- (2)
- (1)
- (1)
- (3)
- (1)
- (2)
- (3)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (5)
- (12)
- (10)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (3)
- (4)
- (1)
- (1)
- (1)
- (7)
- (2)
- (1)
- (2)
- (1)
- (1)
- (5)
- (4)
- (3)
- (1)
- (1)
- (4)
- (6)
- (1)
- (1)
- (1)
- (5)
- (1)
- (1)
- (4)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (2)
- (2)
- (5)
- (2)
- (1)
- (1)
- (1)
- (1)
- (3)
- (14)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (4)
- (1)
- (1)
- (4)
- (5)
- (2)
- (2)
- (1)
- (10)
- (4)
- (1)
- (9)
- (1)
- (8)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (5)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (5)
- (3)
- (4)
- (1)
- (1)
- (3)
- (2)
- (4)
- (1)
- (1)
- (1)
- (1)
- (4)
- (1)
- (5)
- (1)
- (7)
- (1)
- (2)
- (1)
- (7)
- (1)
- (2)
- (1)
- (1)
- (6)
- (1)
- (1)
- (15)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (6)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (1)
- (4)
- (2)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (12)
- (4)
- (2)
- (1)
- (5)
- (1)
- (1)
- (1)
- (3)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (4)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (3)
- (2)
- (6)
- (2)
- (2)
- (1)
- (1)
- (3)
- (1)
- (6)
- (1)
- (5)
- (5)
- (2)
- (1)
- (2)
- (1)
- (7)
- (2)
- (1)
- (1)
- (2)
- (7)
- (5)
- (1)
- (2)
- (5)
- (2)
- (2)
- (1)
- (1)
- (2)
- (3)
- (9)
- (2)
- (1)
- (4)
- (6)
- (9)
- (3)
- (2)
- (1)
- (1)
- (4)
- (3)
- (2)
- (1)
- (4)
- (3)
- (2)
- (7)
- (1)
- (18)
- (16)
- (1)
- (4)
- (2)
- (4)
- (60)
- (5)
- (2)
- (1)
- (1)
- (30)
- (2)
- (2)
- (11)
- (82)
- (12)
- (4)
- (1)
- (3)
- (7)
- (5)
- (1)
- (82)
- (3)
- (378)
- (4)
- (40)
- (21)
- (1)
- (19)
- (1)
- (22)
- (16)
- (1)
- (2)
- (21)
- (2)
- (2)
- (2)
- (1)
- (67)
- (1)
- (1)
- (1)
- (4)
- (8)
- (1)
- (2)
- (2)
- (1)
- (1)
- (4)
- (2)
- (3)
- (2)
- (2)
- (2)
- (2)
- (9)
- (6)
- (8)
- (4)
- (1)
- (1)
- (1)
- (1)
- (2)
- (3)
- (6)
- (3)
- (3)
- (7)
- (2)
- (2)
- (2)
- (7)
- (4)
- (85)
- (1)
- (5)
- (72)
- (3)
- (5)
- (237)
- (4)
- (2)
- (2)
- (21)
- (279)
- (17)
- (1)
- (6)
- (280)
- (28)
- (2)
- (25)
- (2)
- (3)
- (2)
- (2)
- (2)
- (6)
- (3)
- (2)
- (3)
- (48)
- (3)
- (418)
- (6)
- (3)
- (6)
- (5)
- (47)
- (6)
- (3)
- (1)
- (4)
- (21)
- (16)
- (2)
- (4)
- (11)
- (1)
- (8)
- (2)
- (733)
- (11)
- (3)
- (4)
- (2)
- (9)
- (1)
- (2)
- (2)
- (66)
- (2)
- (2)
- (18)
- (3)
- (4)
- (33)
- (2)
- (31)
- (39)
- (2)
- (3)
- (3)
- (3)
- (4)
- (11)
- (3)
- (2)
- (1)
- (3)
- (2)
- (3)
- (2)
- (3)
- (1)
- (3)
- (6)
- (3)
- (2)
- (2)
- (2)
- (3)
- (7)
- (7)
- (1)
- (3)
- (2)
- (3)
- (3)
- (2)
- (1)
- (2)
- (3)
- (3)
- (1)
- (4)
- (3)
- (3)
- (6)
- (5)
- (6)
- (7)
- (3)
- (2)
- (2)
- (3)
- (2)
- (3)
- (2)
- (6)
- (2)
- (1)
- (2)
- (2)
- (1)
- (4)
- (3)
- (4)
- (2)
- (2)
- (2)
- (4)
- (3)
- (1)
- (9)
- (2)
- (2)
- (2)
- (4)
- (1)
- (2)
- (1)
- (7)
- (2)
- (3)
- (2)
- (2)
- (6)
- (2)
- (4)
- (1)
- (11)
- (2)
- (2)
- (4)
- (6)
- (2)
- (4)
- (1)
- (1)
- (4)
- (8)
- (2)
- (3)
- (2)
- (13)
- (6)
- (2)
- (2)
- (14)
- (2)
- (3)
- (1)
- (2)
- (11)
- (1)
- (8)
- (2)
- (5)
- (2)
- (6)
- (2)
- (2)
- (1)
- (1)
- (2)
- (12)
- (2)
- (12)
- (2)
- (2)
- (3)
- (4)
- (9)
- (3)
- (6)
- (3)
- (5)
- (2)
- (7)
- (2)
- (3)
- (12)
- (2)
- (3)
- (3)
- (3)
- (2)
- (5)
- (2)
- (11)
- (1)
- (3)
- (4)
- (1)
- (6)
- (4)
- (2)
- (4)
- (1)
- (2)
- (5)
- (2)
- (2)
- (6)
- (2)
- (2)
- (3)
- (2)
- (2)
- (7)
- (2)
- (2)
- (2)
- (6)
- (3)
- (2)
- (2)
- (3)
- (3)
- (2)
- (2)
- (3)
- (5)
- (3)
- (2)
- (4)
- (4)
- (2)
- (2)
- (2)
- (3)
- (1)
- (7)
- (4)
- (5)
- (3)
- (6)
- (3)
- (2)
- (1)
- (4)
- (2)
- (2)
- (2)
- (3)
- (2)
- (3)
- (2)
- (3)
- (4)
- (2)
- (2)
- (2)
- (8)
- (1)
- (1)
- (2)
- (2)
- (3)
- (6)
- (2)
- (1)
- (3)
- (3)
- (3)
- (2)
- (2)
- (3)
- (2)
- (5)
- (3)
- (1)
- (4)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (4)
- (2)
- (2)
- (3)
- (3)
- (2)
- (3)
- (6)
- (3)
- (2)
- (5)
- (2)
- (1)
- (4)
- (1)
- (12)
- (2)
- (10)
- (2)
- (1)
- (12)
- (3)
- (3)
- (1)
- (3)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (7)
- (3)
- (4)
- (3)
- (1)
- (4)
- (2)
- (3)
- (2)
- (7)
- (4)
- (4)
- (3)
- (5)
- (2)
- (2)
- (2)
- (3)
- (2)
- (3)
- (2)
- (6)
- (1)
- (2)
- (1)
- (3)
- (6)
- (1)
- (4)
- (1)
- (3)
- (1)
- (2)
- (8)
- (2)
- (5)
- (4)
- (1)
- (2)
- (2)
- (1)
- (4)
- (8)
- (3)
- (5)
- (2)
- (6)
- (4)
- (2)
- (2)
- (5)
- (6)
- (2)
- (2)
- (3)
- (3)
- (3)
- (2)
- (5)
- (1)
- (2)
- (3)
- (4)
- (1)
- (7)
- (1)
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- (5)
- (2)
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- (2)
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- (5)
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Filtered Search Results
Medchemexpress LLC Branaplam hydrochloride | 1562338-39-9 | 99.4% | 429.94 | 1 ML
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Branaplam (LMI070; NVS-SM1) hydrochloride is a highly potent, selective, and orally active survival motor neuron-2 (SMN2) splicing modulator. It has an EC50 of 20 nM for SMN and inhibits human-ether-a-go-go-related gene (hERG) with an IC50 of 6.3 μM. This compound is capable of elevating full-length SMN protein and extending survival in a severe spinal muscular atrophy (SMA) mouse model. It is intended for research use only and not for sale to patients.
- Highly potent, selective, and orally active SMN2 splicing modulator.
- Elevates full-length SMN protein.
- Extends survival in a severe spinal muscular atrophy (SMA) mouse model.
- Produces dose-dependent elevations of SMN2-FL transcript and SMN protein in brain and spinal cord.
- Improves body weight and extends lifespan in n SMN∆7 mice.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Pnu 37883 hydrochloride | 57568-80-6
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Pnu 37883 hydrochloride | 57568-80-6
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Medchemexpress LLC IACS-9571 hydrochloride | 2319611-93-1 | 98.3% | 679.22 | 1 MG
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IACS-9571 hydrochloride (ASIS-P040) is a potent and selective inhibitor of TRIM24 and BRPF1. It shows excellent cellular potency with EC50 of 50 nM and potent activities against a panel of 32 bromodomains. It is also highly selective against BRPF2 and BRPF3, and does not interact with the BET sub-family of bromodomains.
- Potent and selective TRIM24 and BRPF1 inhibitor
- Excellent cellular potency (EC50 of 50 nM)
- Potent activities against 32 bromodomains
- High selectivity against BRPF2 and BRPF3
- No interaction with BET sub-family bromodomains
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC W-7 (isomer hydrochloride) | 69762-85-2 | MFCD00151342 | 99.7% | 377.33 g/mol | C16H22Cl2N2O2S | 10 MG
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W-7 (isomer hydrochloride) is the hydrochloride salt of an isomer of W-7, a selective calmodulin antagonist used as a biochemical research reagent to study calmodulin-dependent signaling and related cellular processes. The compound has a molecular weight of 377.33 g/mol and a CAS number of 69762-85-2, and is supplied in high-purity form for laboratory applications.
- High purity (99.65%) suitable for research applications.
- Used as a calmodulin antagonist to probe calmodulin-dependent pathways.
- Available as solid and pre-formulated DMSO solutions for convenience.
- Supplied in small-scale quantities appropriate for research experiments.
- Comes with a safety data sheet and supporting documentation.
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Medchemexpress LLC Alpelisib hydrochloride | 1584128-91-5 | 50 MG
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Alpelisib hydrochloride is a potent, orally active, and selective PI3Kα inhibitor, demonstrating antineoplastic activity. It effectively inhibits the two most prevalent PIK3CA somatic mutations, H1047R and E545K, and suppresses Akt phosphorylation in cells. This compound has shown to inhibit the growth of osteosarcoma cell lines and induce cell cycle arrest in the G0/G1 phase.
- Potent, orally active, and selective PI3Kα inhibitor
- Exhibits antineoplastic activity
- Effectively inhibits PIK3CA somatic mutations H1047R and E545K
- Suppresses Akt phosphorylation in cells
- Inhibits cell growth of osteosarcoma cell lines
- Induces cell cycle arrest in G0/G1 phase
- Significantly reduces tumor volumes in vivo
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Medchemexpress LLC Eglumegad hydrochloride | 176199-48-7 | 99.63% | 221.64 | 5 MG
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Eglumegad hydrochloride is a highly potent and selective group II (mGlu2/3) receptor agonist. It protects neurons from NMDA toxicity and has anxiolytic- and antipsychotic-like effects.
- Highly potent and selective group II (mGlu2/3) receptor agonist.
- Protects neurons from NMDA toxicity.
- Has anxiolytic-like effects.
- Has antipsychotic-like effects.
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Medchemexpress LLC Antalarmin (hydrochloride) | 220953-69-5 | MFCD05664721 | 99.9% | 415.01 g/mol | C24H35ClN4 | 25 MG
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Antalarmin hydrochloride is a research-grade, non-peptide corticotropin-releasing hormone receptor 1 (CRHR1) antagonist supplied as a solid for preclinical pharmacology and biochemical studies. Intended for laboratory research use only.
- High purity (≈99.9%).
- Molecular weight 415.01 g/mol.
- Molecular formula C24H35ClN4.
- Appearance: solid, white to light yellow.
- Storage: sealed at -20°C; in solution: -80°C for 6 months, -20°C for 1 month.
- Supplied with data sheet, certificate of analysis, and safety data sheet.
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Medchemexpress LLC VU0453379 hydrochloride | 98.0% | 471.03 | 25 MG
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VU0453379 hydrochloride is a highly selective and central nervous system (CNS) penetrant positive allosteric modulator (PAM) of glucagon-like peptide-1R (GLP-1R) with an EC50 of 1.3 μM.
- Highly selective
- CNS penetrant
- Positive allosteric modulator (PAM) of GLP-1R
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Medchemexpress LLC BMY-25368 hydrochloride | 86134-36-3 | 97.0% | 379.88 | 5 MG
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BMY-25368 (SKF 94482) is a histamine H2 receptor antagonist that acts as a gastric acid secretion inhibitor. It competitively antagonizes gastric secretion stimulated by histamine, Pentagastrin, Bethanechol, and food. This product is for research use only and not intended for medical applications.
- Acts as a histamine H2 receptor antagonist
- Inhibits gastric acid secretion
- Antagonizes gastric secretion stimulated by histamine, Pentagastrin, Bethanechol, and food
- Light yellow to yellow solid
- Suitable for laboratory research
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Medchemexpress LLC Adrogolide hydrochloride | 166591-11-3 | 99.6% | 435.96 | C22H26ClNO4S | 25 MG
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Adrogolide hydrochloride is a research-grade prodrug converted rapidly in plasma to the dopamine D1 receptor agonist A-86929. Supplied as the hydrochloride salt, it is intended for laboratory research use only and is provided in pre-weighed quantities for assay preparation.
- High purity (≈99.6%) suitable for research applications.
- Molecular weight 435.96 and formula C22H26ClNO4S.
- Available in pre-weighed small quantities for in vitro and in vivo studies.
- Soluble in DMSO for assay preparation.
- Acts as a prodrug to the D1 receptor agonist A-86929.
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Medchemexpress LLC Oxyfedrine hydrochloride | 16777-42-7 | 99.9% | 349.85 | C19H24ClNO3 | 50 MG
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Oxyfedrine hydrochloride is an orally active β-adrenoreceptor agonist and coronary vasodilator supplied as the hydrochloride salt for research use. It is intended for pharmacological and cardiovascular studies and should be stored and handled according to supplier recommendations.
- High purity for research applications (99.9% as listed).
- Molecular formula C19H24ClNO3 and molecular weight 349.85.
- Supplied as a solid, facilitating handling and formulation.
- Storage: sealed, away from moisture and light; in solvent -80°C (6 months) or -20°C (1 month).
- Suitable for studies of β-adrenergic activity and coronary vasodilation.
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Medchemexpress LLC Amiloride hydrochloride | 2016-88-8 | 99.8% | 25 MG
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Amiloride hydrochloride is an analytical standard intended for research and analytical applications. It acts as an inhibitor of both epithelial sodium channel (ENaC) and urokinase-type plasminogen activator receptor (uTPA), and is also identified as a blocker of the polycystin-2 (PC2; TRPP2) channel. This compound is commonly used as a reference standard in qualitative, quantitative, and methodological research experiments.
- Used as an analytical standard
- Inhibits epithelial sodium channel (ENaC)
- Inhibits urokinase-type plasminogen activator receptor (uTPA)
- Blocks polycystin-2 (PC2; TRPP2) channel
- Suitable for HPLC, GC, and MS experiments
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Medchemexpress LLC Slm6031434 hydrochloride | 1897379-34-8 | 99.1% | 5MG
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Slm6031434 hydrochloride | 1897379-34-8 | 99.1% | 5MG
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Medchemexpress LLC CCG258208 hydrochloride | 98.1% | 488.94 | 25 MG
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CCG258208 (GRK2-IN-1) hydrochloride is a potent and selective inhibitor of GRK2 (G protein-coupled receptor kinase 2) with an IC50 of 30 nM. It demonstrates significant selectivity, being 230-fold more selective over GRK5 (IC50=7.09 μM) and over 2500-fold more selective over GRK1 (IC50=87.3 μM), PKA, and ROCK1. This compound is utilized in heart failure research.
- Potent and selective GRK2 inhibitor (IC50=30 nM).
- High selectivity over GRK5 (230-fold).
- Even higher selectivity over GRK1, PKA, and ROCK1 (more than 2500-fold).
- Applicable in heart failure research.
- Shows significant improvement in βAR-stimulated contractility in mouse cardiomyocytes at concentrations as low as 0.1 μM.
- Exhibits a superior half-life *in vivo*.
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Medchemexpress LLC Fadrozole hydrochloride (CGS 16949A) | 102676-31-3 | 99.9% | C14H14ClN3 | 50 MG
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Fadrozole hydrochloride (CGS 16949A) is a potent, selective, and nonsteroidal inhibitor of aromatase with an IC50 of 6.4 nM. It inhibits estrogen production in hamster ovarian slices with an IC50 of 0.03 μM and progesterone production with an IC50 of 120 μM. Higher doses can suppress the synthesis of other cytochrome P-450 dependent steroids to varying degrees.
- Potent and selective aromatase inhibitor.
- Prevents development of benign and malignant spontaneous mammary neoplasms.
- Slows development of pituitary pars distalis adenomas and reduces incidence of spontaneous hepatocellular tumors.
- Reduces parasite burden in male and female mice by 70%.
- Augments Interleukin-6 (IL-6) serum levels and production by splenocytes.
- Nonsteroidal option for aromatase inhibition.
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